Adult Niemann-Pick disease type C in France: clinical phenotypes and long-term miglustat treatment effect.

Orphanet J Rare Dis · 2018 · PMC6167825 · PMID 30285904

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an increasing trendno p-value reported

Indeed, since 2012, there has been an increasing trend to speak of an adolescent/adult neurological onset form (although keeping the same age at onset).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.