Structures reveal opening of the store-operated calcium channel Orai.

Elife · 2018 · PMC6170153 · PMID 30160233

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highly significantno p-value reported

This paper is highly significant for providing insights into the mechanism of pore opening and the first view of the open pore structure of the Orai channel which suggests mechanisms underlying ion permeation and selectivity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.