Genome-wide association studies and CRISPR/Cas9-mediated gene editing identify regulatory variants influencing eyebrow thickness in humans.

PLoS Genet · 2018 · PMC6171961 · PMID 30248107

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP = 4.95×10 −11actually significant

However, the signal at 3q22.3, which was highly significant in CANDELA, with P = 4.95×10 −11 at rs112458845 and an effect allele frequency (EAF) of 0.127, did not reach nominal significance in our GWAS of TZL (EAF = 0.065, P = 0.729) and UYG (EAF = 0.032, P = 0.494).

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