C-3- and C-4-Substituted Bicyclic Coumarin Sulfamates as Potent Steroid Sulfatase Inhibitors.

ACS Omega · 2018 · PMC6173509 · PMID 30320251

Europe PMC DOI

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highly significantno p-value reported

Some of these ( 29 , 32 , 41 , and 42 ) have a potency approaching the clinical drug Irosustat in the more definitive intact MCF-7 cell assay, and of these, 29 is highly significant with a similar picomolar IC 50 .

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