DILI caused by medications such as ximelagatran, lapatinib, ticlopidine or amoxicillin with clavulanate acid are found to be associated with variants of human leukocyte antigens (HLAs), indicating that adaptive immune response might be significant for hepatotoxicity induced by those drugs.
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Models of Drug Induced Liver Injury (DILI) - Current Issues and Future Perspectives.
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