Population Pharmacokinetic Analysis for Daclatasvir and Asunaprevir in Japanese Subjects With Chronic Hepatitis C Virus Infection.

J Clin Pharmacol · 2018 · PMC6174986 · PMID 30063254

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highly significantno p-value reported

In addition, the time‐varying effect was assessed for AST and ALT on CL/F and was highly significant compared with incorporating only baseline AST and ALT values, with a decrease of ‐139.192 and ‐108.05, respectively.

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