It Is Time to Meet the Challenges of the Changing Epidemiology of Gastroesophageal Reflux Disease.

5 Similarly, a recent US study based on the Cerner Health Facts database (including 35 000 000 patients from January 2001 to December 2010), showed an increasing trend in the prevalence of GERD, BE, and esophageal adenocarcinoma (EAC) with increasing age. 6 On the contrary, a US study conducted with 476 individuals, which mainly included male veterans who were undergoing endoscopy for upper gastrointestinal symptoms, showed that the prevalence and severity of eso

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