Immunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis mice highly susceptible to light damage.

Quantification of these SD-OCT thickness maps revealed a highly significant retinal thinning ( P <0.001) for Cln3 Δex7/8 animals at a light exposure of 10,000 lux for 30 min at days 4 and 7 ( Fig. 2 B).

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