Novelty enhances memory persistence and remediates propranolol-induced deficit via reconsolidation.

Novelty facilitates memory persistence through behavioral tagging during memory reactivation and reconsolidation In Experiment 1, a highly significant linear decline of latency to retrieving all rewards was seen across 12 training sessions ( Fig. 1 B, F 1,15 = 20.81, p < 0.0001).

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The difference between these two time delays was marginally significant (t 15 = 2.12, p = 0.051).

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