The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation.

Cancer Cell · 2018 · PMC6179967 · PMID 30300583

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an overall trendno p-value reported

Primary t(8;21)-negative AML cells showed an overall trend of being less sensitive to palbociclib compared with t(8;21)-positive AML ( Figures 7 A and S7 D), although there was some heterogeneity in response concomitant with reported sensitivity in other AML subtypes ( Placke et al., 2014 , Uras et al., 2016 , van der Linden et al., 2015 ).

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