At the protein level, the HMOX-1 protein showed a highly significant increase in the VV2 subtype brains, and the PRDX3 protein showed a significant elevation in both the subtypes of sCJD brains.
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p62-Keap1-NRF2-ARE Pathway: A Contentious Player for Selective Targeting of Autophagy, Oxidative Stress and Mitochondrial Dysfunction in Prion Diseases.
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