Selective depletion of metastatic stem cells as therapy for human colorectal cancer.

EMBO Mol Med · 2018 · PMC6180303 · PMID 30190334

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highly significantno p-value reported

These effects associated with a reduction in CXCR4 + target cancer cell fraction in tumor tissue, being both the antimetastatic effect and the reduction in CXCR4 + CCF highly significant in LV, LG, and PTN Mets, whereas they were non‐significant in primary tumor or LN Mets.

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