Barely Significant
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Ca2+ binding induced sequential allosteric activation of sortase A: An example for ion-triggered conformational selection.

PLoS One · 2018 · PMC6188747 · PMID 30321208

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highly significantno p-value reported
The increase of 3.4 °C in T m with Ca 2+ is highly significant and provides experimental evidence for our theoretical observation that calcium stabilizes the Sa-SrtA structure.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.