Deletion of the HD (AntpΔHD) decreased dramatically the interaction with TFIIEβ; only 26% of the AntpΔHD cells showed a highly significant difference in interaction compared to 78% of the cells with wild-type Antp and 75% with AntpHD ( Fig 1A and 1B ; S1 Fig ).
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Transcription factor TFIIEβ interacts with two exposed positions in helix 2 of the Antennapedia homeodomain to control homeotic function in Drosophila.
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