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Diverse Biological Functions of Sphingolipids in the CNS: Ceramide and Sphingosine Regulate Myelination in Developing Brain but Stimulate Demyelination during Pathogenesis of Multiple Sclerosis.

J Neurol Psychol · 2017 · PMC6190913 · PMID 30338269

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an increasing trendno p-value reported
GlcCer is the initial Monoglycosylceramide (MGC) that appears at early Postnatal stage (P8) and then GalCer appears at P10 with an increasing trend until P21 and its concentration remains unaltered.

also in 63,971 other papers

a decreasing trendno p-value reported
Total Cer level showed a decreasing trend in NAWM (0.75-fold) and MS plaque (0.65-fold; data not shown).

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.