Global long non-coding RNA expression in the rostral anterior cingulate cortex of depressed suicides.

Along with our findings that lncRNAs are associated with overlapping and antisense genes involved in IFN signaling, lncRNA associations with distal protein-coding genes also involved in immune and neurological processes implicate lncRNAs in regulating immune signals that may be significant players underlying depression and suicide.

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We found highly significant correlations between RNA-seq and RT-qPCR expression values for each lncRNA across the 50 samples (Supplementary Table 6 ), indicating high reliability across these experimental approaches.

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