In a multivariable logistic regression analysis the change in TGF-β1 remained borderline significant, OR 0.91 (95% CI 0.82–1.00) when age, hypertension and mean heart dose were included in the model (Additional file 5 : Table S5).
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Decreases in TGF-β1 and PDGF levels are associated with echocardiographic changes during adjuvant radiotherapy for breast cancer.
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