Quantitative Approaches to Assess Key Carcinogenic Events of Genotoxic Carcinogens.

Toxicol Res · 2018 · PMC6195881 · PMID 30370003

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an expected trendno p-value reported

5 , the genotoxic carcinogenesis pathway showed an expected trend where BMDL 10 s was low in the early stages of carcinogenesis: DNA adduct <<mutation < GST-P positive foci < cancer ( 12 ).

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