Barely Significant
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Antioxidant bilirubin works in multiple ways to reduce risk for obesity and its health complications.

Open Heart · 2018 · PMC6196942 · PMID 30364545

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highly significantno p-value reported
81 82 In one of these trials, the patients ingested 6 g spirulina daily for 6 months; at the end of the study, liver enzymes had dropped by about a third, serum lipid profile had improved (lower triglycerides and LDL-C, higher HDL-C), insulin resistance assessed by HOMA had dropped by 20% and BMI had dropped by 8%—changes that were all highly significant. 82 Since the patients had not been asked to modify their diets or exercise habits, the observed weight loss conceivably could be attributable to an improvement in hypothalamic inflammation.

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