Although there was no clear difference between them, except for better transfection efficiency and immune response in group C (VRB2B3-PEG-O-CS-PEI), all 5 carriers resulted in highly significant increased antibacterial bioactivity in HEK293 cells and enhancements of immunity both pre- and post-challenge.
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Improved expression of recombinant fusion defensin gene plasmids packed with chitosan-derived nanoparticles and effect on antibacteria and mouse immunity.
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