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Impact of the Myosin Modulator Mavacamten on Force Generation and Cross-Bridge Behavior in a Murine Model of Hypercontractility.

J Am Heart Assoc · 2018 · PMC6201428 · PMID 30371160

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an increasing trendP =0.07so close (0.05 < p ≤ 0.1)
However, at pCa 6.0, P1 was unaffected following Myk461 incubations in WT myocardium but showed an increasing trend ( P =0.07) following 1.0 μmol/L Myk461 incubation in KO myocardium (Tables 3 and 4 ).

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