Beneficial effects of intravenous iron therapy in a rat model of heart failure with preserved systemic iron status but depleted intracellular cardiac stores.

successfully increased body iron stores, which was indicated by increase of hepatic iron content by almost 10-fold both in sham operated and HF rats, but was not excessive, since it only mildly increased serum ferritin and free iron concentration; increase of myocardial iron content amounted to no more than approximately 20% in HF, while in sham operated rats failed to reach significance.

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