Semimechanistic Population Pharmacokinetic Model to Predict the Drug-Drug Interaction Between S-ketamine and Ticlopidine in Healthy Human Volunteers.

CPT Pharmacometrics Syst Pharmacol · 2018 · PMC6202471 · PMID 30091858

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a slight trendno p-value reported

A slight trend in the norketamine model fit at the inhibitor phase can be attributed to the fast metabolism to secondary metabolites, but also to the marked between‐subject variability in the S ‐ketamine metabolism.

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