The miR-503 cluster is coordinately under-expressed in endometrial endometrioid adenocarcinoma and targets many oncogenes, cell cycle genes, DNA repair genes and chemotherapy response genes.

Onco Targets Ther · 2018 · PMC6203085 · PMID 30425513

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highly significantno p-value reported

Using normalized expression values (ΔCt) for each miRNA in all 24 individuals in the panel, including the benign tissues, pairwise correlation among all five members of the cluster reveals a highly significant pattern of coordinated expression across the entire cluster.

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