highly significantp < 0.0001
Key Findings • The mean percent decrease from baseline in ulcer area over the treatment period was highly significant for both the collagenase ( p < 0.0001) and for the silver ( p < 0.0001) treatment groups. • Ulcers treated with clostridial collagenase had a 55% greater mean reduction in area from baseline when compared with the silver control group at the end of treatment ( p = 0.071). • Silver treatment provide