While expression of transcription factors involved in activating innate immune responses, including interferon regulatory factors (IRF) 1,2,5,7 and 8 was highly significant in P. falciparum , only IRF 1,7 and 9 were significantly up-regulated upon exposure to P. vivax .
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Malaria systems immunology: Plasmodium vivax induces tolerance during primary infection through dysregulation of neutrophils and dendritic cells.
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