We identified causative mutations in almost 40% of families with a family history of SRNS or CKD compared to only 6% of patients with SRNS and no family history, a difference that was highly significant and makes a positive family history of SRNS or CKD the single most important clinical predictor of mutation amongst patients with SRNS.
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Genetic Testing for Steroid-Resistant-Nephrotic Syndrome in an Outbred Population.
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