The fact that we did not find differences between salivary and plasma IgA1 O -glycosylation, except for a slight trend of lower sialylation in saliva, is likely due to their inherently different biosynthetic pathways as compared to N -glycans, involving distinct glycosyltransferases ( 61 ).
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Comparative Glycomics of Immunoglobulin A and G From Saliva and Plasma Reveals Biomarker Potential.
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