a marginal trendP = 0.014
The relative abundance of the genus Bilophilia was significantly lower in the lower Q group than in the upper Q group (CE, 0.0045; P = 0.004; q = 0.043) and showed a marginal trend toward decrease compared with the middle 2Q group (CE, 0.0034; P = 0.014; q = 0.098; Fig. 5B ).