Chemotherapeutic Efficacy of Implantable Antineoplastic-Treatment Protocols in an Optimal Mouse Model for Human Ovarian Carcinoma Cell Targeting.

MUC16 expression in pre and post-treatment groups using both drugs (methotrexate and cisplatin) was up-regulated and displayed an increasing trend in the placebo (4.31–5.11%), AF(D)NMs (6.13–6.36%) and IV-drug groups (7.67–8.14%) ( p < 0.05), whilst in the NMs (D) group, MUC16 expression was down-regulated (2.67–3.3%) ( Figure 11 ).

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The study of the flow properties was considered extremely significant to this study as it is central to the mechanisms by which the ISFI functions.

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