highly significantP < 0.0001
Two biological replicates were analyzed for all conditions (i.e., n = 2 per condition), and highly significant ( P < 0.0001) Pearson correlation coefficient values were obtained for each replicate set ( r = 0.9 and 0.855 for p65 ChIP replicates; r = 0.849 and 0.85 for BMAL1 ChIP replicates, and r = 0.890 and 0.888 for CLOCK ChIP replicates in saline and LPS conditions, respectively) ( Supplemental Fig.