Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome.

Transl Neurodegener · 2018 · PMC6218962 · PMID 30410750

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.1200

boldest claim

The sentences

an increasing trendp = 0.09so close (0.05 < p ≤ 0.1)

In addition, this result is supported by an increasing trend (not significant, p = 0.09) for LC3 gene expression in Ts65Dn treated with rapamycin (Fig. 3I ).

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a decreasing trendp = 0.12not close (p > 0.1)

A decreasing trend (not significant) for working memory errors (50%; p = 0.12) was evident in Ts65Dn treated with InRapa (Fig. 2f ) compared to Ts65Dn Veh.

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