highly significantP = 0.048
Finally, we demonstrated that patients with increased levels of CD8 + PD-1 hi cells (above the median) were more likely to develop recurrence of their disease compared with those with low levels of CD8 + PD-1 hi (below the median), with a highly significant P value of 0.0009, with an unadjusted HR of 4.3 (95% CI, 1.02–18.23; P = 0.048).