Estrogen promotes the onset and development of idiopathic scoliosis via disproportionate endochondral ossification of the anterior and posterior column in a bipedal rat model.

Exp Mol Med · 2018 · PMC6220154 · PMID 30405118

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a decreasing trendno p-value reported

The circulating serum estrogen levels in rats increased from week 1 to week 7, but after week 7, a decreasing trend was observed.

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