Gene annotation and ontology BED files consisting of highly significant TRP47 peaks were submitted to Genomic Regions Enrichment of Annotations Tool (GREAT) version 3.0 [ 16 ].
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Ehrlichia chaffeensis TRP47 enters the nucleus via a MYND-binding domain-dependent mechanism and predominantly binds enhancers of host genes associated with signal transduction, cytoskeletal organization, and immune response.
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