Moreover, the mRNA levels of Acc1 , Pgc-1α , Ppar-γ , and Ucp-1 were all downregulated by an increase in eT in both genotypes of mice, while mRNA levels of hormone-sensitive lipase ( Hsl ) and lipoprotein lipase ( Lpl ) showed a numerical trend towards diminished expression in dwarf mice.
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Increased environmental temperature normalizes energy metabolism outputs between normal and Ames dwarf mice.
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