Conversely, E4 detection (≥ 5%) was more frequent in CIN1 and normal/nil/no biopsy but just failed to reach statistical significance (p = 0.06).
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Risk stratification of cervical disease using detection of human papillomavirus (HPV) E4 protein and cellular MCM protein in clinical liquid based cytology samples.
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0.0600
The sentences
Despite these caveats, as predicted by the previous tissue-based study, high MCM detection was associated with CIN2+ and E4 association with <=CIN1 was close to significance.