borderline significantP = .046
Three studies ( Supplementary Material; Hoffman 1986, Gasem 1995, Wain 2008 ) previously examined the relationship between sample volume and blood culture sensitivity directly, but one of these studies did not find conclusive evidence to support the hypothesized relationship ( Supplementary Material, Gasem 1995 ) and another ( Supplementary Material, Hoffman 1986 ) was borderline significant ( P = .046 by Pearson’s χ 2 test).