highly significantP < 0.05
A P value of less than 0.05 was considered statistically significant, and a P value of less than 0.01 was considered highly significant (*, P < 0.05; **, P < 0.01; ***, P < 0.001).
A P value of less than 0.05 was considered statistically significant, and a P value of less than 0.01 was considered highly significant (*, P < 0.05; **, P < 0.01; ***, P < 0.001).