Abstracts of the 11th International Conference on Cachexia, Sarcopenia and Muscle Wasting, Maastricht, The Netherlands, 7–9 December 2018

Conclusions: Our results suggest that emergent defects in nucleocytoplasmic transport and in the integrity of the nuclear barrier may contribute to age‐related motoneuron death and therefore these events may be significant indirect drivers skeletal muscle loss. 1–65 Myofibre death is not a major contributor to age‐related skeletal muscle atrophy Navneet Lal 1 , Jon Cornwall 2 and Philip Sheard 1 1 Department of Physiology, Otago University, Dunedin, New Zealand; 2 Centre for Early Learning in Medicine, Otago University, Dunedin, New Zealand Introduction: Age‐related skeletal muscle atrophy is thought to result partly from loss of myofibres.

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