When FMR1 mRNA levels were used as the predictor, highly significant associations between the level of this transcript and all wmhs scores were seen in both FXTAS and Total samples, before and after adjustment for multiple comparisons.
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The Spectrum of Neurological and White Matter Changes and Premutation Status Categories of Older Male Carriers of the <i>FMR1</i> Alleles Are Linked to Genetic (CGG and FMR1 mRNA) and Cellular Stress (AMPK) Markers.
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