Hyper-phosphorylation of Rb S249 together with CDK5R2/p39 overexpression are associated with impaired cell adhesion and epithelial-to-mesenchymal transition: Implications as a potential lung cancer grading and staging biomarker.

We believe this finding is highly significant, not only for its potential for being clinically informative, but also because currently there is a scarcity of prognostic signatures for SCC patients, the majority of lung cancer prognosis signatures identified to date being for the AC subtype [ 96 , 97 ].

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