Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence.

BMC Genomics · 2018 · PMC6245894 · PMID 30453884

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highly significantno p-value reported

[ 10 ] have identified three highly significant haplotype tagging SNPs, namely rs16969968 (haplotype A), rs588765 (haplotype B), and rs6495308 (haplotype C, protective), of which haplotype A and C yielded the strongest signals.

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