Strikingly, iron contents varied among different zones within each lobe, although no very convincing common rule could be defined for all lobes when considered individually (Figure 1 E); however, there was an overall trend of gradient decrease of LIC from zones near the entrance site of the portal vein and hepatic artery to the distal end region of the liver.
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Distinct Iron Deposition Profiles of Liver Zones in Various Models with Iron Homeostasis Disorders.
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