The clinical significance of FAM19A4 methylation in high-risk HPV-positive cervical samples for the detection of cervical (pre)cancer in Chinese women.

BMC Cancer · 2018 · PMC6263049 · PMID 30486875

Europe PMC DOI

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highly significantP < 0.05actually significant

A highly significant trend for increasing FAM19A4 methylation with increasing histological severity (Cochran-Armitage trend test, P < 0.05), which were 10.61% (7/66), 35.48%(11/31), 56.14%(32/57), and 93.44% (57/61) in the no CIN, LSIL, HSIL, and cervical cancer groups respectively.

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