TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.

Nat Cell Biol · 2018 · PMC6268100 · PMID 30420664

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highly significantno p-value reported

Strikingly, however, TNF/MRT co-treatment resulted in highly significant reduction in survival, with 50% lethality only 8.5 hours after injection and an overall survival of less than 20%.

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