Barely Significant
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3-Phenylcoumarins as inhibitors of HIV-1 replication.

Molecules · 2012 · PMC6268528 · PMID 22858844

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highly significantno p-value reported
Considering that simple changes in structure promote highly significant changes in bioactivity, further research should take into account these findings for the preparation of more potent and selective inhibitors of the NF- κ B and Tat viral pathways.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.