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18F-labeled pyrazolo[1,5-a]pyrimidine derivatives: synthesis from 2,4-dinitrobenzamide and tosylate precursors and comparative biological evaluation for tumor imaging with positron emission tomography.

Molecules · 2012 · PMC6268720 · PMID 22453929

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an increasing trendno p-value reported
In Vivo biodistribution studies in mice bearing S180 tumors showed that the uptake of both [ 18 F] 3 and [ 18 F] 4 in tumors displayed an increasing trend while the uptake of [ 18 F] 5 in tumor decreased through the course of the 120 min study.

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