Improving the fermentation production of the individual key triterpene ganoderic acid me by the medicinal fungus Ganoderma lucidum in submerged culture.

X 3 (culture time) had extremely significant effect on GA-Me production ( P < 0.01), followed by x 2 (peptone concentration), suggesting culture time and peptone concentration are very important for GA-Me production in submerged fermentation of G. lucidum .

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The Fisher’s F-test with a very low probability value [( P model > F ) = 0.0002] for the total model indicated the model was highly significant.

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