Treatment of FGE at the two higher doses significantly up-regulated both mRNA and protein expressions of renal organic cation/carnitine transporters, except that FGE at 278 mg/kg failed to reach significance despite increased renal protein levels of mOCTN1.
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Fructus Gardenia Extract ameliorates oxonate-induced hyperuricemia with renal dysfunction in mice by regulating organic ion transporters and mOIT3.
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